Tzu-Ching Chang Selected Research

Acetylserotonin O-Methyltransferase (Hydroxyindole O Methyltransferase)

10/2021	Association of Tumor Hydroxyindole O-Methyltransferase and Serum 5-Methoxytryptophan with Long-Term Survival of Hepatocellular Carcinoma.
1/2018	Restoration of hydroxyindole O-methyltransferase levels in human cancer cells induces a tryptophan-metabolic switch and attenuates cancer progression.

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Tzu-Ching Chang Research Topics

Disease

10	Neoplasms (Cancer) 10/2021 - 10/2009
7	Hepatocellular Carcinoma (Hepatoma) 10/2021 - 10/2009
3	Hypoxia (Hypoxemia) 03/2020 - 06/2005
3	Neoplasm Metastasis (Metastasis) 01/2011 - 10/2009
2	Carcinogenesis 02/2022 - 03/2014
2	Breast Neoplasms (Breast Cancer) 10/2021 - 01/2010
2	Fibrosis (Cirrhosis) 01/2021 - 03/2016
2	Ischemia 03/2020 - 06/2005
2	Inflammation (Inflammations) 01/2015 - 03/2014
1	Stomach Neoplasms (Stomach Cancer) 02/2022
1	Adenocarcinoma 02/2022
1	Thymoma (Thymic Carcinoma) 02/2022
1	Mitochondrial Diseases (Mitochondrial Disease) 02/2022
1	Overweight 02/2022
1	Chronic Renal Insufficiency 01/2021
1	Infarction (Infarctions) 01/2020
1	Myocardial Infarction 01/2020
1	Myocardial Ischemia (Ischemic Heart Diseases) 01/2020
1	Hyperglycemia 01/2015
1	Multiple Myeloma 12/2010
1	Lymphoma (Lymphomas) 12/2010
1	Lung Neoplasms (Lung Cancer) 01/2010
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2010
1	Edema (Dropsy) 07/2007

Drug/Important Bio-Agent (IBA)

3	Tryptophan (L-Tryptophan)FDA Link 10/2021 - 03/2014
3	Focal Adhesion Protein-Tyrosine KinasesIBA 05/2013 - 10/2009
2	Glucose (Dextrose)FDA LinkGeneric 02/2022 - 01/2015
2	Biomarkers (Surrogate Marker)IBA 10/2021 - 01/2011
2	5-methoxytryptophanIBA 10/2021 - 01/2018
2	Acetylserotonin O-Methyltransferase (Hydroxyindole O Methyltransferase)IBA 10/2021 - 01/2018
2	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2020 - 11/2005
2	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2020 - 06/2005
2	Proteins (Proteins, Gene)FDA Link 01/2011 - 06/2005
2	Proteasome InhibitorsIBA 12/2010 - 01/2010
2	Bortezomib (Velcade)FDA Link 12/2010 - 01/2010
1	mitochondrial transcription factor AIBA 02/2022
1	Mitochondrial DNA (mtDNA)IBA 02/2022
1	HexokinaseIBA 02/2022
1	Oxidoreductases (Dehydrogenase)IBA 02/2022
1	Pyruvic Acid (Pyruvate)IBA 02/2022
1	Messenger RNA (mRNA)IBA 10/2021
1	NitrogenIBA 01/2021
1	CreatinineIBA 01/2021
1	prolinedithiocarbamate (PDTC)IBA 01/2021
1	Urea (Carbamide)FDA LinkGeneric 01/2021
1	MetallothioneinIBA 01/2021
1	Coloring Agents (Dyes)IBA 01/2020
1	ChloridesIBA 01/2020
1	TransferasesIBA 01/2020
1	Biotin (Vitamin H)FDA Link 01/2020
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2020
1	Protein Isoforms (Isoforms)IBA 01/2018
1	Matrix Metalloproteinases (MMPs)IBA 06/2016
1	CytokinesIBA 03/2016
1	Cisplatin (Platino)FDA LinkGeneric 03/2016
1	Oxidants (Oxidizing Agents)IBA 01/2015
1	CateninsIBA 06/2014
1	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 06/2014
1	5-methoxyindoleIBA 03/2014
1	MelatoninIBA 03/2014
1	Fetal Proteins (Fetoprotein)IBA 01/2011
1	Boronic AcidsIBA 12/2010
1	benzyloxycarbonylleucyl-leucyl-leucine aldehydeIBA 01/2010
1	SteroidsIBA 07/2007
1	Hormones (Hormone)IBA 07/2007
1	Cyclooxygenase 1IBA 11/2005
1	CatalaseIBA 11/2005
1	Epoprostenol (Prostacyclin)FDA LinkGeneric 11/2005
1	4- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA 11/2005
1	NADPH Oxidases (NAD(P)H oxidase)IBA 11/2005
1	Hypoxia-Inducible Factor 1IBA 11/2005
1	Caspase 3 (Caspase-3)IBA 06/2005
1	Cytochromes c (Cytochrome c)IBA 06/2005

Therapy/Procedure

2	Therapeutics 01/2011 - 10/2009
1	Gastrectomy 02/2022
1	Organ Transplantation 01/2020
1	Chemoprevention 03/2014